Natural Non-Trasgenic Animal Models for Research in Alzheimers Disease
نویسندگان
چکیده
منابع مشابه
Natural Non-Trasgenic Animal Models for Research in Alzheimer’s Disease
The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human Abeta precursor protein (APP) and/or some of the enzymes implicated in their metabolic processing. However, these transgenic mice carry their own APP and APP-processing enzymes, which may interfere in the production of different amyloid-beta (Abeta) peptides e...
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Edison P Reyes1,2, Paula P Cortés3 and Ricardo Fernández3* 1Centro de Fisiología Celular e Integrativa, Facultad de Medicina, Clínica Alemana-Universidad del Desarrollo, Chile 2Dirección de Investigación, Universidad Autónoma de Chile, Chile 3Departamento de Salud, Universidad de Los Lagos, Chile *Corresponding author: Ricardo Fernández, Departamento de Salud, Universidad de Los Lagos. Av. Fuch...
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ژورنال
عنوان ژورنال: Current Alzheimer Research
سال: 2009
ISSN: 1567-2050
DOI: 10.2174/156720509787602834